Spectrophotometric Simultaneous Determination of Valsartan and Amlodipine Besylate in Combined Capsule Dosage form by Ratio Derivative Method
نویسندگان
چکیده
منابع مشابه
Three Multivariate Calibration Methods for Simultaneous Spectrophotometric Determination of Olmesartan Medoxamil, Amlodipine Besylate and Hydrochlorothiazide in Their Combined Dosage Form
Olmesartan medoxamil (OLM, an angiotensin II receptor blocker), amlodipine besylate (AML, a dihydropyridine calcium channel blocker) and hydrochlorothiazide (HCT, a diuretic of the class of benzothiadiazines) are co-formulated in a single-dose combination for the treatment of hypertensive patients whose blood pressure is not adequately controlled on either component monotherapy. In this work, t...
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A novel, simple, accurate, sensitive, reproducible, economical spectroscopic method has been developed and validated for the determination of Nebivolol hydrochloride and S-amlodipine besylate in combined dosage form. The method obeys Beer’s Law in concentration range of 15-35 μg/ml for Nebivolol and 7.5-17.5 μg/ml for S-amlodipine. The method was validated for linearity, range, accuracy, precis...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Research
سال: 2010
ISSN: 2454-8405,0973-7200
DOI: 10.18579/jpcrkc/2010/9/4/79504